A quantitative model of error accumulation during PCR amplification
نویسندگان
چکیده
منابع مشابه
A quantitative model of error accumulation during PCR amplification
The amplification of target DNA by the polymerase chain reaction (PCR) produces copies which may contain errors. Two sources of errors are associated with the PCR process: (1) editing errors that occur during DNA polymerase-catalyzed enzymatic copying and (2) errors due to DNA thermal damage. In this study a quantitative model of error frequencies is proposed and the role of reaction conditions...
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ژورنال
عنوان ژورنال: Computational Biology and Chemistry
سال: 2006
ISSN: 1476-9271
DOI: 10.1016/j.compbiolchem.2005.11.002